• A chalazion is a chronic inflammatory granuloma of a meibomian gland. It appears to be caused by alterations in secretions with retention of secretory material due to obstruction of {the} ducts.
  • Chalazia originating in {the} Zeis sebaceous glands are termed "external chalazia"; those in {the} meibomian glands of {the} tarsus are termed "internal chalazia."

Associated Conditions

  • seborrhea
  • chronic blepharitis
  • acne rosacea.


  • soft tissue swelling
  • erythema
  • firm nodule



  • As {the} gland fills with oily secretions, it increases in size over weeks.
  • The lesion most commonly is seen to bulge externally through {the} skin and less commonly through {the} conjunctiva.
  • It might remain contained within {the} tarsus or break through anteriorly beneath {the} skin or on {the} conjunctival side, inducing pyogenic granuloma formation.


  • medical treatment consists of warm compresses and topical antibiotic ointment.
  • When {the} chalazion does not respond to more conservative medical management after 2 weeks, or when {the} lesion is large and symptomatic, surgical excision is indicated.
  • Once excised, continued treatement with warm compresses is generally helpful
  • Once excised, treatment with an antibiotic-steroid ointment such as
    also helps resolution of {the} chalazion


  • It should be emphasized that any atypical or recurrent chalazion must be regarded as a possible neoplastic lesion and should be biopsied.
  • Basal cell carcinoma, squamous cell carcinoma, and adenocarcinoma of {the} meibomian glands all have been mistaken for chalazia; these are Malignant ( Malignancy is {the} tendency of a cancer or tumor either to invade {the} surrounding tissues, to destroy or replace {the} tissues previously present or to metastasize (spread to other parts of {the} body) tumors.
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