What is Symblepharon?
A symblepharon is a fibrous tract that connects bulbar conjunctiva toconjunctiva on {the} eyelid.
Symblepharon, Normal Fornix
Symblepharon, Upper Fornix
When do symblepharon occur?
- Cicatricial pemphigoid; auto-immune disease which affects mucus membranes such as {the} mouth and oral pharynx, conjunctiva, nares and genitalia
- Atopic keratoconjunctivitis: This is a hypersensitivity to environmental allergies including asthma, rhinitis, dermatitis and eczema.
- Trichiasis: A lid abnormality in which eyelashes are misdirected towards {the} eyeball. These misdirected lashes might possibly often be {the} result of scarring.
- Toxic epidermal necrosis (TEN): A potentially life-threatening disorder which is commonly drug-induced.
- Stevens Johnson Syndrome
- Characteristics:
- Equal age and sex distribution
- Substantial disease associated with a 5-15% mortality rate
- Ocular involvement in 50%
- Associated with various infections and medications most notably sulfa
- Pathogenesis:
- Angiitis-->Erythematous lesion-->Bullae-->Rupture-->Scar
- Prodrome:
- Fever, chills, and headache
- 7 days later bullous mucosal lesions develop
- Sequelae:
- Problems are related to {the} destruction of Goblet cells and a lack of conjunctival mucus which leads to keratinization and scarring.
- Lid scarring with symblepharon
- Corneal scarring
- Keratitis sicc
- Characteristics:
- Burns
- Erythema multiforme: This is an acute multi-cutaneous hypersensitivity reaction
What are {the} treatment options?
- Why use Amniotic membrane? Because it:
- facilitates epithelialization
- maintains normal epithelial phenotype (with goblet cells when performed on conjunctiva ),
- reduce inflammation, vascularization and scarring.
The use of human amniotic membrane for {the} surgical treatment of an ocular surface disorder was originally reported by de Rotth 16 in 1940. During {the} 1990s, {the} role of amniotic membrane transplantation in treating a variety of ocular surface defects and abnormalities has been revived.
Chemical Burns
Pterygium
Corneal/Sclera Ulceration &
Peforations
Tumors
Stevens-Johnson's Syndrome
Procedures
- Home
- Anophthalmos
- Blepharoplasty
- Blepharospasm
- Brow Lift
- Congenital
- Dry Eye
- Eyelid Laxity
- Face
- Infections
- Inflammation
- Lacrimal System
- Lagophthalmos
- Latisse
- Locate an MD
- Orbital Tumors
- Ptosis
- Skin Rejuvenation
- Skin Tumors
- Symblepharon
- Thyroid
- Trauma